Protein Purification
MilliporeSigma™ Calbiochem™ Granzyme B Substrate II, Fluorogenic
A fluorogenic substrate for the detection of granzyme B and caspase-8 activity.
MilliporeSigma™ Calbiochem™ HIF Inhibitor VII
A cell-permeable benzoxadiazolamine that prevents HIF-2α-HIF-β/ARNT heterodimeration by perturbing HIF-2α Per-ARNT-Sim/PAS-B domain surface β-sheet conformation via a 1:1 stoichiometric binding ( K D = 81nM), while exhibiting no affinity toward HIF-1αPAS-B
MilliporeSigma™ Calbiochem™ Apigenin
Induces the reversion of transformed phenotypes of v-H-ras-transformed NIH 3T3 cells at low concentration (12.5 μM).
MilliporeSigma™ Calbiochem™ LSD1 Inhibitor VII, SP-2509
A cell-permeable, potent, selective, reversible inhibitor of Lysine-Specific Demethylase 1 (LSD1; IC50 = 13 nM; Ki = 31 nM).
MilliporeSigma™ Calbiochem™ CCR2 Antagonist
The CCR2 Antagonist, also referenced under CAS 445479-97-0, controls the biological activity of CCR2.
MilliporeSigma™ Calbiochem™ Indirubin-3'-monoxime-5-sulphonic Acid
A potent, reversible, and selective inhibitor of Cdk1 (IC50 = 5 nM) and Cdk5 (IC50 = 7 nM) and glycogen synthase kinase-3β (GSK-3β; IC50 = 80 nM).
MilliporeSigma™ Calbiochem™ eIF4E/eIF4G Interaction Inhibitor II, 4E1RCat
The eIF4E/eIF4G Interaction Inhibitor II, 4E1RCat controls the biological activity of eIF4E/eIF4G interaction. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
MilliporeSigma™ Calbiochem™ Histone Acetyltransferase Inhibitor II
The Histone Acetyltransferase Inhibitor II, also referenced under CAS 932749-62-7, controls the biological activity of Histone Acetyltransferase. This small molecule/inhibitor is primarily used for Cell Structure applications.
MilliporeSigma™ Calbiochem™ MMP-2/MMP-9 Inhibitor II
The MMP-2/MMP-9 Inhibitor II, also referenced under CAS 193807-60-2, controls the biological activity of MMP-2/MMP-9. This small molecule/inhibitor is primarily used for Protease Inhibitors applications.
MilliporeSigma™ Calbiochem™ p-APMSF, Hydrochloride
Alternative to DFP and PMSF.
MilliporeSigma™ Calbiochem™ RHC-80267
Selective inhibitor of DAG lipase activity in canine platelets (IC50 = 4 nM) and in a variety of mammalian cells.
MilliporeSigma™ Calbiochem™ InSolution™ H-89, Dihydrochloride
InSolution™ H-89, Dihydrochloride, CAS 127243-85-0, is a 10mm solution of H-89, 2HCl in DMSO. A cell-permeable, potent, reversible, ATP-competitive inhibitor of protein kinase A (Ki = 48nM).
Gibco™ Expi293™ Inducible Expression System Kit
Expi293 Inducible Expression System Kit is part of the Expi293 platform for rapid, high-yield transient protein expression from mammalian 293 cells
